Key result
Adjuvant radiotherapy to a total dose of 60 Gy was administered with good tolerance in a 59-year-old male with primary intimal cardiac sarcoma following wide local excision with positive margins.
Why the study?
Primary cardiac sarcoma is rare with poor prognosis, and no randomized controlled trials or standard management guidelines exist.
Is adjuvant radiotherapy safe and well-tolerated in patients with primary intimal cardiac sarcoma after wide local excision?
Case Report (n=1)
Is adjuvant radiotherapy safe and well-tolerated in patients with primary intimal cardiac sarcoma after wide local excision?
Adjuvant radiotherapy up to 60 Gy was well tolerated in a patient with primary intimal cardiac sarcoma following wide local excision with positive margins.
Supports adjuvant radiotherapy after positive-margin resection in cardiac intimal sarcoma; extends Level 2 evidence for this rare malignancy.
Background: Primary cardiac sarcoma (PCS) is a rare malignancy, and intimal cardiac sarcoma is the rarest. The prognosis is poor with mean survival of 3–12 months even with complete radical resection. There has been no randomised controlled trial or standard guidelines for management of cardiac sarcomas. Treatment is extrapolated from case reports and series. Case presentation: A 59-year-old male diagnosed with primary intimal cardiac sarcoma underwent wide local excision with positive margins. Adjuvant radiotherapy to a total dose of 60 Gray (Gy) was given with good tolerance. Conclusions: Intimal cardiac sarcoma is rare. The risk of local recurrence is high, and efforts must be made to elucidate the role and usefulness of radiotherapy and chemotherapy in these tumours.
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Al-Hajri et al. (2021) conducted a case report in Primary intimal cardiac sarcoma (n=1). Adjuvant radiotherapy was evaluated on Tolerance. Adjuvant radiotherapy to a total dose of 60 Gy was administered with good tolerance in a 59-year-old male with primary intimal cardiac sarcoma following wide local excision with positive margins.
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