Key result
In a 20-year-old female with advanced cardiac angiosarcoma and pulmonary metastasis, palliative chemotherapy with doxorubicin and ifosfamide yielded limited response, resulting in death six months after presentation.
Why the study?
Cardiac angiosarcoma is a rare and aggressive malignant tumor with a poor prognosis, underscoring the need to highlight early diagnosis and multidisciplinary management.
Case Report (n=1)
This case highlights the presentation and diagnosis of a rare and aggressive cardiac angiosarcoma with pulmonary metastasis in a young patient.
Prompts inclusion of angiosarcoma in differentials for young adults with dyspnea; extends sparse Level 5 reports but leaves management questions open.
Cardiac angiosarcoma is a rare and aggressive malignant tumor arising from the endothelial cells of the heart. It accounts for only a small fraction of all cardiac neoplasms and has a poor prognosis. We present a challenging case of a 20-year-old student who presented exertional dyspnea, palpitation, and occasional chest discomfort. Her clinical picture, radiological and pathological investigations confirm the diagnosis of cardiac angiosarcoma with pulmonary metastasis. This case highlights the importance of early diagnosis and multidisciplinary management for improved patient outcomes.
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Agboola et al. (2023) conducted a case report in Cardiac angiosarcoma with pulmonary metastasis (n=1). Doxorubicin and ifosfamide was evaluated. In a 20-year-old female with advanced cardiac angiosarcoma and pulmonary metastasis, palliative chemotherapy with doxorubicin and ifosfamide yielded limited response, resulting in death six months after presentation.
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