Preclinical evaluation demonstrates higher signal intensity and prolonged retention of RDP in tumor imaging, suggesting potential as an advanced dual-targeted MRI contrast agent.
MRI assays were carried out. It has been proven that RDP has higher relaxivity of aqueous solution than Magnevist used in clinics. Moreover, RDP achieved higher signal intensity and a longer signal duration in tumor imaging. Therefore, RDP can be applied as the potential dual-targeted MRI CA for clinical tumor diagnosis.
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Yu et al. (2024) studied this question.
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