Key result
Diabetes mellitus significantly reduces the chaotic response of heart rate variability compared to non-diabetic controls (P<0.03).
Why the study?
Can chaotic global parameters of HRV distinguish between diabetic and non-diabetic subjects?
Observational (n=46)
Can chaotic global parameters of HRV distinguish between diabetic and non-diabetic subjects?
p-value: p=<0.03
Diabetes reduces the chaotic response of heart rate variability, suggesting it acts as a dynamical condition similar to cardiac arrest or epilepsy.
May distinguish diabetic autonomic changes; hypothesis-generating and should not yet change practice.
This study's aim is to analyze heart rate dynamics in subjects with diabetes by measures of heart rate variability (HRV). The correlation of chaotic global parameters in the two cohorts is able to assess the probability of cardiac failure and other dynamical diseases. Adults (46) were divided into two equal groups. The autonomic evaluation consisted of measuring HRV for 30 min in supine position in absence of any physical, sensory, or pharmacological stimuli. Chaotic global parameters are able to statistically determine which series of electrocardiograph interpeak intervals in short time‐series are diabetic and which are not. The chaotic forward parameter that applies all three parameters is suggested to be the most appropriate and robust algorithm. This was decided after tests for normality; followed by one‐way analysis of variance (ANOVA1); (P < 0.09) and Kruskal–Wallis technique (P < 0.03). Principal component analysis implied two components represent 99.8% of total variance. Therefore, diabetes is a disease which reduces the chaotic response and, as such may be termed a dynamical condition such as are cardiac arrest, asthma, and epilepsy.
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Souza et al. (2014) conducted an observational in Diabetes mellitus (n=46). Diabetes mellitus vs. Non-diabetic adults was evaluated on Chaotic global parameters of heart rate variability (p=<0.03). Diabetes mellitus significantly reduces the chaotic response of heart rate variability compared to non-diabetic controls (P<0.03).
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