Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance2011 · 45 citations
2. 2Reduced beta-cell glucose transporter in new onset diabetic BB rats.1990 · 95 citations
3. 3β-Cell-specific inactivation of the mouse<i>Ipf1/Pdx1</i> gene results in loss of the β-cell phenotype and maturity onset diabetes1998 · 922 citations
4. 4Glucose uptake, utilization, and signaling in GLUT2-null islets.2000 · 151 citations
5. 5Overexpression of SIRT1 Protects Pancreatic β-Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor-κB Signaling Pathway2008 · 348 citations