What question did this study set out to answer?

To evaluate whether driving pressure-oriented ventilation improves intraoperative respiratory physiology and clinical outcomes in patients undergoing one-lung ventilation during thoracic surgery.

May 27, 2022Frontiers in SurgeryOpen Access

Effect of Driving Pressure-Oriented Ventilation on Patients Undergoing One-Lung Ventilation During Thoracic Surgery: A Systematic Review and Meta-Analysis

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Authors

XLXuan LiUniversity of British Columbia WXWenqiang XueKunming Medical University QZQinyu ZhangHunan University of Traditional Chinese Medicine

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Implication

Meta-analysis reveals reduced pulmonary complications and improved oxygenation during one-lung ventilation, indicating clear physiological benefits.

Key Points

To evaluate whether driving pressure-oriented ventilation improves intraoperative respiratory physiology and clinical outcomes in patients undergoing one-lung ventilation during thoracic surgery.
Systematic search across MEDLINE, Embase, Cochrane, Web of Science, and ClinicalTrials.gov (PROSPERO CRD42021297063).
Meta-analysis synthesizing seven studies comprising a total of 640 patients undergoing one-lung ventilation.
Primary outcome was the PaO2/FiO2 ratio, with secondary outcomes including postoperative pulmonary complications, respiratory compliance, and mean arterial pressure.
Driving pressure-oriented ventilation significantly increased the intraoperative PaO2/FiO2 ratio (MD: 44.96; 95% CI, 24.22–65.70; P < 0.0001).
The incidence of postoperative pulmonary complications was significantly lower in the driving pressure group (OR: 0.58; 95% CI, 0.34–0.99; P = 0.04).
Respiratory system compliance improved significantly (MD: 6.15; 95% CI, 3.97–8.32; P < 0.00001), with no significant change in mean arterial pressure.

Cite This Study

Li et al. (2022) studied this question.

synapsesocial.com/papers/6aa2a5f0d081bdd435a72f6a https://doi.org/10.3389/fsurg.2022.914984

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Implication

Meta-analysis reveals reduced pulmonary complications and improved oxygenation during one-lung ventilation, indicating clear physiological benefits.

Effect of Driving Pressure-Oriented Ventilation on Patients Undergoing One-Lung Ventilation During Thoracic Surgery: A Systematic Review and Meta-Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Effect of Driving Pressure-Oriented Ventilation on Patients Undergoing One-Lung Ventilation During Thoracic Surgery: A Systematic Review and Meta-Analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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