What is the clinical evidence from this study?

Study design: Other. Population: Avian heart development. Intervention: Developmental stage (embryonic to adult). Primary outcome: Expression of myosin heavy chain (MHC) isoforms.

June 1, 1988Developmental BiologyOpen Access

Developmental patterns of expression and coexpression of myosin heavy chains in atria and ventricles of the avian heart

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Key result

Expression of 3 embryonic MHC isoforms becomes regionally restricted in the adult avian heart.

Authors

DEDonnie EvansStanford University JMJeffrey B. MillerThe Wistar Institute FSFrank E. StockdaleStanford University

Discussion

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Implication

Avian MHC patterns should not inform human care; extends developmental biology but leaves open mammalian translation.

PICO

Population

Avian heart development

Exposure / Comparator

Developmental stage (embryonic to adult)

Primary Outcome

Expression of myosin heavy chain (MHC) isoforms

Cite This Study

Evans et al. (1988) studied Avian heart development. Developmental stage (embryonic to adult) was evaluated on Expression of myosin heavy chain (MHC) isoforms. In the developing avian heart, at least three MHC isoforms are expressed in both atria and ventricles embryonically, but in adults, expression becomes restricted to specific regions.

synapsesocial.com/papers/6aa2c22a74fc654bd0323ccc https://doi.org/10.1016/0012-1606(88)90324-7

View Full Paper

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Developmental patterns of expression and coexpression of myosin heavy chains in atria and ventricles of the avian heart

Discussion

Member takes

Implication

PICO

Cite This Study

Developmental patterns of expression and coexpression of myosin heavy chains in atria and ventricles of the avian heart

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider