Key result
A 79-year-old male on rivaroxaban for atrial fibrillation developed a spontaneous retrobulbar hemorrhage resulting in permanent vision loss.
Case Report (n=1)
Highlights the rare but severe risk of spontaneous retrobulbar hemorrhage associated with rivaroxaban use.
May warrant vigilance for rare ocular bleeds on rivaroxaban; single case leaves open incidence and risk-factor questions.
A retrobulbar hemorrhage is a rapidly worsening emergent condition characteristically associated with significant orbital or facial trauma. Spontaneous hemorrhage into the retrobulbar compartment is rare. If not managed in a timely manner, it can lead to permanent vision loss. Rivaroxaban is a directly acting oral anticoagulant (DOAC) that inhibits factor Xa and is widely used for stroke prevention in patients with non-valvular atrial fibrillation (AFib).
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Jain et al. (2019) conducted a case report in Atrial fibrillation, spontaneous retrobulbar hemorrhage (n=1). Rivaroxaban was evaluated. A 79-year-old male on rivaroxaban for atrial fibrillation developed a spontaneous retrobulbar hemorrhage resulting in permanent vision loss.
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