Key result
Decreasing kidney function was associated with a progressively increased risk of significant coronary lesion complexity as measured by the SYNTAX Score (P = .001).
Why the study?
Is chronic kidney disease associated with higher SYNTAX scores in patients with left main and/or 3-vessel coronary artery disease?
Observational (n=217)
Is chronic kidney disease associated with higher SYNTAX scores in patients with left main and/or 3-vessel coronary artery disease?
p-value: p=.001
Worsening renal function is strongly associated with increased coronary lesion complexity as measured by the SYNTAX score in patients with severe coronary artery disease.
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May warrant integrated cardio-renal risk assessment; extends observational links but leaves open prospective validation.
Çoşkun et al. (2011) conducted an observational in Left main coronary artery and/or 3-vessel coronary artery disease (n=217). Decreasing kidney function (lower eGFR) vs. Normal kidney function (eGFR >90 mL/min per 1.73 m2) was evaluated on Significant lesion complexity (SYNTAX Score) (p=.001). Decreasing kidney function was associated with a progressively increased risk of significant coronary lesion complexity as measured by the SYNTAX Score (P = .001).
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