Key result
Rotational long-axis MRI yields ~30% greater myocardial coverage than short-axis MRI with preserved image quality.
Why the study?
Does rotational long-axis (RLA) myocardial perfusion imaging improve myocardial coverage compared to conventional parallel short-axis (PSA) acquisitions in volunteers?
Observational (n=12)
Does rotational long-axis (RLA) myocardial perfusion imaging improve myocardial coverage compared to conventional parallel short-axis (PSA) acquisitions in volunteers?
Rotational long-axis MRI improves myocardial coverage and delineation of basal and apical regions compared to conventional parallel short-axis imaging.
May improve coverage in volunteer perfusion MRI; hypothesis-generating and requires patient validation before clinical consideration.
PURPOSE: To study a first-pass myocardial perfusion imaging method, such that long-axis imaging slices are obtained rotationally around the short-axis centroid of the left ventricular cavity, in order to improve myocardial coverage and better delineate the basal and apical myocardium. MATERIALS AND METHODS: This rotational long-axis (RLA) method was examined in 12 volunteers and compared to the perfusion images from conventional parallel short-axis (PSA) acquisitions in terms of the contrast to noise ratio (CNR), relative signal upslope and myocardial coverage. Both RLA and PSA first-pass perfusion images were acquired on each volunteer with otherwise identical imaging parameters using the partial Fourier saturation recovery steady state gradient echo sequence with refocused magnetization (TrueFISP) technique. RESULTS: Compared to PSA, RLA perfusion images with identical imaging parameters on the same subject exhibit an average of near 30% improvement in total myocardial area imaged. In addition, true basal and apical myocardium was seen on RLA, but not on PSA. The mean CNR and relative upslope were similar between the two techniques. CONCLUSIONS: This RLA perfusion imaging scheme is superior to the conventional PSA approach in terms of extent myocardial coverage and delineation of basal and apical regions of the left ventricle.
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Wang et al. (2005) conducted an observational in Healthy volunteers (n=12). Rotational long-axis (RLA) MRI vs. Conventional parallel short-axis (PSA) MRI was evaluated on Total myocardial area imaged, contrast to noise ratio (CNR), and relative signal upslope. Rotational long-axis MRI improved total myocardial area imaged by nearly 30% compared to conventional parallel short-axis MRI, while maintaining similar contrast-to-noise ratio and relative upslope.
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