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May 28, 2009Arthritis & RheumatismOpen Access

Gene–environment interaction between the DRB1 shared epitope and smoking in the risk of anti–citrullinated protein antibody–positive rheumatoid arthritis: All alleles are important

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Authors

ELEmeli LundströmKarolinska University HospitalHKHenrik KällbergPublic Health Agency of Sweden
Lars Alfredsson
Lars AlfredssonPreventive Cardiology

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Lundström et al. (2009) studied this question.

synapsesocial.com/papers/6aa2eca1abff4220a6a8a0a5https://doi.org/10.1002/art.24572
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Revised Criteria for the Classification of Rheumatoid Arthritis1990 · 7,736 citations
  2. 2A gene–environment interaction between smoking and shared epitope genes in HLA–DR provides a high risk of seropositive rheumatoid arthritis2004 · 680 citations
  3. 3TRAF1–C5 as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study2007 · 832 citations