Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device
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Key result
Continuous flow LVAD facilitated myocardial recovery and successful explantation in a severe peripartum cardiomyopathy case.
- n=1
Population
1 patient with severe peri-partum cardiomyopathy (PPCM)
Design
Case_report
Authors
Discussion
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Member takes
Implication
Suggests LVAD unloading may enable recovery in peripartum cardiomyopathy; hypothesis-generating and should not yet change practice.
Study Design
Type
Case Report (n=1)
Multicenter
No
Structured PICO
P
Population
A 37-year-old woman with severe peri-partum cardiomyopathy and cardiogenic shock who underwent continuous flow left ventricular assist device implantation and subsequent explantation after myocardial recovery.
I
Intervention
Continuous flow left ventricular assist device (LVAD)
O
Outcome
Cardiac reverse remodelling and recovery permitting explantation of the device
Continuous flow LVADs can provide sustained unloading leading to cardiac reverse remodelling and recovery in severe peri-partum cardiomyopathy, permitting device explantation.
Limitations
- Single case report
- Unpredictability of recovery and prognosis after explant
- PPCM patients may have more severe right ventricular disease limiting LVAD benefits
Cite This Study
Lund et al. (2011) conducted a case report in Peri-partum cardiomyopathy (n=1). Continuous flow left ventricular assist device (HeartMate II) was evaluated on Myocardial recovery and LVAD explantation. A continuous flow left ventricular assist device facilitated myocardial recovery and successful device explantation in a 37-year-old woman with severe peri-partum cardiomyopathy.
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