What question did this study set out to answer?

To characterize the computed tomographic (CT) and cerebral angiographic features across various histologically confirmed intracranial germ cell tumor subtypes.

January 1, 1984Neurologia medico-chirurgicaOpen Access

Intracranial Germ Cell Tumors with Special Emphasis on Computed Tomography and Cerebral Angiography

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To characterize the computed tomographic (CT) and cerebral angiographic features across various histologically confirmed intracranial germ cell tumor subtypes.
Reviewed clinical, CT, and cerebral angiographic findings from N=14 patients (13 males, 1 female; age range 5–34 years) with histologically verified tumors.
Evaluated findings across tumor subtypes, comprising teratoma (n=6), germinoma (n=5), and embryonal carcinoma (n=3).
Plain CT demonstrated perifocal edema exclusively in embryonal carcinoma, while germinomas were uniformly hyperdense in solid regions and teratomas were predominantly isodense with frequent calcification.
Intravenous iodine contrast CT elicited marked tumor enhancement in all embryonal carcinomas and most teratomas, but only slight enhancement in germinomas.
Cerebral angiography revealed abnormal tumor vessels and dense staining in embryonal carcinoma, whereas these findings were absent in teratomas and only faintly present in rare germinoma cases.

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Implication

Case series reveals distinct computed tomography and angiographic features among intracranial germ cell tumor subtypes in young patients, indicating imaging can aid histologic differentiation.

Cite This Study

Imai et al. (1984) studied this question.

synapsesocial.com/papers/6aa2ef3224af305511206bec https://doi.org/10.2176/nmc.24.767

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Implication

Case series reveals distinct computed tomography and angiographic features among intracranial germ cell tumor subtypes in young patients, indicating imaging can aid histologic differentiation.

Intracranial Germ Cell Tumors with Special Emphasis on Computed Tomography and Cerebral Angiography

Key Points

Discussion

Implication

Cite This Study

Intracranial Germ Cell Tumors with Special Emphasis on Computed Tomography and Cerebral Angiography

Key Points

Discussion

Implication

Cite This Study

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