Transcriptome Analysis of Three Sheep Intestinal Regions reveals Key Pathways and Hub Regulatory Genes of Large Intestinal Lipid Metabolism

Figures

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  Figure 1. Clustered heat map showing the expression patterns of transcripts differentially expressed between the duodenum and the large intestine.

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  Figure 2. KEGG pathways achieved significant enrichment levels in all four enrichment analyzes. D: Duodenum higher expressed genes; L: Large intestine higher expressed genes.

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  Figure 3. Protein-protein interaction networks of metabolism related pathway enriched genes. The node size was decided on the basis of the interaction degree value of each gene. Triangle node: FPKM < 10 in all intestinal regions; Circular node: 10 ≤ FPKM < 500 in at least one tissue with the highest expression; Square node: FPKM ≥ 500 in at least one intestinal tissue. Red: Higher expressed in the duodenum; Blue: Higher expressed in the large intestine; Green: Multiple transcript expression patterns are not consistent.

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  Figure 4. Clustered heat map showing the expression patterns of transcripts differentially expressed between the cecum and the colon.

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  Figure 5. KEGG pathways achieved significant enrichment between the cecum and colon at both the FPKM ≥ 1 and FPKM ≥ 10 level. Cecum: Cecum higher expressed genes; Colon: Colon higher expressed genes.

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  Figure 6. Protein-protein interaction networks of lipid metabolism related pathway enriched genes. The node size was decided on the basis of the interaction degree value of each gene. Triangle node: FPKM < 10 in either the cecum or colon; Circular node: 10 ≤ FPKM < 500 in the tissue with the highest expression; Square node: FPKM ≥ 500 in at least one intestinal tissue. Red: Higher expressed in colon; Blue: Higher expressed in cecum; Green: Multiple transcript expression patterns are not consistent.