What question did this study set out to answer?

To investigate the source and successfully control an outbreak of nosocomial Burkholderia cepacia complex sepsis within a neonatal intensive care unit.

June 22, 2020Journal of Medical Case ReportsOpen Access

Investigation of Burkholderia cepacia complex bacteremia outbreak in a neonatal intensive care unit: a case series

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Authors

TBTanisha BhararaJohn Hunter Hospital ACAnita ChakravartiThe Ohio State University MSMukesh SharmaShree Guru Gobind Singh Tricentenary University

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Implication

Case series reveals a multidrug-resistant Burkholderia cepacia outbreak linked to suction equipment in neonates, highlighting the critical role of rapid infection control and strict hygiene.

Key Points

To investigate the source and successfully control an outbreak of nosocomial Burkholderia cepacia complex sepsis within a neonatal intensive care unit.
Conducted an epidemiological outbreak investigation following the detection of Burkholderia cepacia complex in blood cultures of admitted neonates.
Collected environmental surveillance samples and performed phenotypic characterization, including biotyping and antimicrobial susceptibility testing.
Clinical isolates demonstrated multidrug resistance, retaining in vitro susceptibility exclusively to meropenem with a minimum inhibitory concentration of 4 μg/ml.
Burkholderia cepacia complex was isolated from a neonatal intensive care unit suction apparatus, with environmental isolates matching clinical isolates identically by biotype and susceptibility.
The outbreak was successfully curtailed following rapid alert notification, environmental source identification, and reinforced hand hygiene and disinfection measures.

Cite This Study

Bharara et al. (2020) studied this question.

synapsesocial.com/papers/6aa2fc934eb0fe97dac22807 https://doi.org/10.1186/s13256-020-02415-8

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Implication

Case series reveals a multidrug-resistant Burkholderia cepacia outbreak linked to suction equipment in neonates, highlighting the critical role of rapid infection control and strict hygiene.

Investigation of Burkholderia cepacia complex bacteremia outbreak in a neonatal intensive care unit: a case series

Discussion

Member takes

Implication

Key Points

Cite This Study

Investigation of Burkholderia cepacia complex bacteremia outbreak in a neonatal intensive care unit: a case series

Discussion

Member takes

Implication

Key Points

Cite This Study

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