February 1, 1998Cardiovascular Surgery
Coronary Bypass with Arterial Conduits
Key result
Multi-arterial grafting is a safe procedure for myocardial revascularization, as choice of conduit was not a predictor of operative mortality or morbidity by multivariate analysis.
Why the study?
Does multi-arterial grafting compared to single arterial or venous grafting affect operative mortality and morbidity in patients undergoing myocardial revascularization?
Population
3,062 patients undergoing myocardial revascularization (CABG)
Comparison
Myocardial revascularization with two or more… vs Single internal mammary artery ± veins or only…
Design
Cohort
Follow-up
Operative (perioperative)
Authors
Discussion
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Member takes
Implication
Supports multi-arterial grafting safety in selected patients; leaves open randomized confirmation of outcomes.
Study Design
Type
Cohort (n=3,062)
Structured PICO
Does multi-arterial grafting compared to single arterial or venous grafting affect operative mortality and morbidity in patients undergoing myocardial revascularization?
P
Population
3,062 patients undergoing myocardial revascularization with multi-arterial, single internal mammary artery, or saphenous vein conduits.
E
Exposure
Myocardial revascularization with two or more arterial conduits (Group M, n=368)
C
Comparator
Single internal mammary artery ± veins (Group S, n=2092) or only saphenous vein conduits (Group V, n=602)
O
Outcome
Operative mortalityhard clinical
Main Result
p-value: p=<0.001
Multi-arterial grafting is a safe and efficacious procedure for myocardial revascularization in carefully selected patients, without independently increasing operative mortality or morbidity compared to conventional conduits.
Limitations
- Long-term survival and freedom from reoperation require further study
Cite This Study
Rizzo et al. (1998) conducted a cohort in Myocardial revascularization (n=3,062). Multi-arterial grafting (two or more arterial conduits) vs. Single internal mammary artery ± veins, or only saphenous vein conduits was evaluated on Operative mortality (p=<0.001). Multi-arterial grafting is a safe procedure for myocardial revascularization, as choice of conduit was not a predictor of operative mortality or morbidity by multivariate analysis.