Case report demonstrates successful recovery from Naegleria fowleri infection in an adolescent, highlighting early miltefosine therapy and intracranial pressure control.
Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.
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Linam et al. (2015) studied this question.
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