A unipolar depressed patient developed a fast-cycling bipolar disorder on abrupt discontinuation of long-term treatment with a tricyclic antidepressant. The case illustrates the potential for drug withdrawal to induce mood disturbance that is more severe than the original illness.
No takes yet. Share an insight, caveat, or question.
Jones et al. (1984) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: