A new alkaloid, kopreasin A (1) was isolated from the leaves of Kopsia arborea (Apocynaceae) together with ten known indole alkaloids (2 -11), and the structure was elucidated by NMR spectral analysis using 2D techniques.These indole alkaloids showed a moderate vasorelaxant activity on isolated rat aorta ring.
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Morita et al. (2008) studied this question.
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