Key result
Intravenous heparin therapy resulted in symptomatic improvement and a reduction in the size of bilateral ventricular thrombi in a patient with septic cardiomyopathy.
Case Report (n=1)
No
This case highlights the rare occurrence of bilateral ventricular thrombi in septic cardiomyopathy and emphasizes the utility of advanced imaging techniques like CMR for accurate diagnosis.
Single case suggests possible heparin benefit for thrombi in septic cardiomyopathy; hypothesis-generating and should not yet change practice.
Right ventricular thrombus (RVT) is a rare but clinically significant condition associated with severe complications, such as pulmonary embolism and right heart failure. This case report presents a 68-year-old woman with a history of diabetes, coronary artery disease, and heart failure with reduced ejection fraction (HFrEF), who developed bilateral ventricular thrombi in the context of septic cardiomyopathy secondary to a diabetic foot infection and a urinary tract infection (UTI). Echocardiography revealed thrombi in both the right and left ventricles, severe global hypokinesia, and reduced ejection fraction. The patient was treated with intravenous heparin and showed symptomatic improvement. Diagnostic challenges in RVT were highlighted, emphasizing the limitations of echocardiography in differentiating cardiac masses and the superior diagnostic capabilities of cardiac magnetic resonance imaging (CMR). This case underscores the importance of early diagnosis, individualized management strategies, and the utility of advanced imaging techniques in RVT.
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Chaaban et al. (2025) conducted a case report in Bilateral ventricular thrombi and septic cardiomyopathy (n=1). Intravenous heparin was evaluated on Symptomatic improvement and thrombus resolution. Intravenous heparin therapy resulted in symptomatic improvement and a reduction in the size of bilateral ventricular thrombi in a patient with septic cardiomyopathy.
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