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Observational study reveals elevated placental and fetal bone lead concentrations following maternal occupational exposure, highlighting severe fetal bioaccumulation risks.
The lead values in maternal and infant blood, in placental tissue, and in stillbirth liver, kidney, and rib- and skull-bones have been determined in samples from the Stoke-on-Trent area. The lead values in antenatal blood and placenta increase with occupational exposure; liver and kidney stillbirth lead values are lower than those of much older children and rib-bone lead values from stillbirths were on average three times as high as those from a control group comprised of cot deaths and early infant deaths from accidental causes.
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Khera et al. (1980) studied this question.
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