Key result
Negative inotropes treat dynamic LVOT obstruction in HCM caused by mitral valve systolic anterior motion.
This review highlights the flow drag mechanism of systolic anterior motion in hypertrophic cardiomyopathy and outlines medical and interventional treatment strategies for dynamic left ventricular outflow obstruction.
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Supports negative inotropy for dynamic LVOTO in HCM; extends flow-drag mechanism of SAM yet leaves open need for prospective validation.
Mark V. Sherrid (1998) conducted a review in Hypertrophic cardiomyopathy. Dynamic left ventricular outflow obstruction in hypertrophic cardiomyopathy is caused by systolic anterior motion of the mitral valve and is generally treatable with negatively inotropic drugs.
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