Key result
Patient-prosthesis mismatch is not linked to increased hospital mortality.
Why the study?
Does patient-prosthesis mismatch affect early operative mortality and perioperative complications in patients undergoing isolated aortic valve surgery?
Cohort (n=193)
Does patient-prosthesis mismatch affect early operative mortality and perioperative complications in patients undergoing isolated aortic valve surgery?
Absolute Event Rate: 5% vs 2.4%
p-value: p=0.855
Patient-prosthesis mismatch is common in isolated aortic valve surgery but does not significantly impact early postoperative mortality or complications.
Patient-prosthesis mismatch does not appear to raise early mortality after AVR; leaves open its long-term effects and optimal sizing.
AIM: The mains topics of this work are the incidence of patient-prosthesis mismatch and the influence in the early results of isolated aortic valve surgery. METHODS: In 193 patients isolated aortic valve surgery was performed. The study population was divided in three subgroups: 20 patients with severe, 131 patients with moderate and 42 patients without patient-prosthesis mismatch. The indexed effective orifice area was used to define the subgroups. Operative mortality and perioperative complications were considered the indicators of the early results of aortic valve surgery. RESULTS: The incidence of severe and moderate patient-prosthesis mismatch was respectively 10.3% and 67.8%. Hospital mortality and perioperative complications were: mortality 5% vs. 3.1% vs. 2.4% (p = 0.855), low cardiac output 5% vs. 6.9% vs. 4.8% (p = 0.861); pulmonary complications 5% vs. 3.1 vs. 0.0% (p = 0.430); exploration for bleeding 5% vs. 0.8% vs. 2.4% (p = 0.319); atrial fibrillation 30% vs. 19.8% vs. 11.9% (p = 0.225); wound infection 5% vs. 0.8% vs. 0.00% (p = 0.165), respectively for the group with severe, moderate and without patient-prosthesis mismatch. CONCLUSIONS: Patient-prosthesis mismatch is a common occurrence in aortic valve surgery. This phenomenon does not affect the early results of aortic valve surgery.
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Dumani et al. (2014) conducted a cohort in Isolated aortic valve surgery (n=193). Patient-prosthesis mismatch vs. No patient-prosthesis mismatch was evaluated on Hospital mortality (p=0.855). Patient-prosthesis mismatch was common but did not significantly affect hospital mortality compared to no mismatch (5% severe vs 3.1% moderate vs 2.4% none; P=0.855).
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