Key result
Epidural morphine is linked to less postoperative delirium versus systemic analgesia in elderly orthopedic patients.
Why the study?
Does epidural morphine administration reduce the frequency of postoperative delirium in elderly patients undergoing lower limb orthopedic surgery compared to systemic analgesia?
Cohort (n=113)
Does epidural morphine administration reduce the frequency of postoperative delirium in elderly patients undergoing lower limb orthopedic surgery compared to systemic analgesia?
Epidural administration of 3 mg morphine may significantly reduce the incidence of postoperative delirium in elderly patients undergoing major lower limb orthopedic surgery compared to systemic analgesia.
May support epidural morphine to lower postoperative delirium risk in elderly orthopedic patients; leaves open confirmation via randomized trials.
The aim of the study was to reduce the frequency of postoperative delirium development in elderly and elderly patients who underwent operative intervention on the hip and knee joints, acetabulum, tubular bones of the lower limb by epidural morphine administration. Materials and methods: a retrospective analysis of the medical records of 113 patients of the Department of Traumatology and Orthopedics was performed, during which two groups of patients were compared, in one of which epidural analgesia was supplemented with the administration of 3 mg of morphine epidurally, in the second, regional anesthesia combined with a systemic introduction of analgesics; the obtained data were processed using statistical analysis methods. Conclusion: the study found that in patients who underwent analgesia by epidural administration of 3mg of 1% morphine solution, the frequency of postoperative delirium development was significantly lower than in the group with systemic analgesia.
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Sokolov et al. (2018) conducted a cohort in Postoperative delirium (n=113). Epidural morphine vs. Regional anesthesia with systemic analgesics was evaluated on Frequency of postoperative delirium. In 113 elderly orthopedic patients, epidural administration of 3 mg of morphine significantly reduced the frequency of postoperative delirium compared to systemic analgesia.
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