Key result
Endoleaks detected in only one phase of follow-up CT (arterial or delayed) had a significantly higher rate of spontaneous resolution than those detected in both phases (87.5% vs 50.0%; p=0.006).
Why the study?
Does the phase of CT detection (arterial vs delayed) predict the clinical outcome of endoleaks after endovascular repair of abdominal aortic aneurysm?
Observational (n=144)
Does the phase of CT detection (arterial vs delayed) predict the clinical outcome of endoleaks after endovascular repair of abdominal aortic aneurysm?
Absolute Event Rate: 87.5% vs 50%
p-value: p=0.006
Endoleaks detected only in the delayed phase of CT after EVAR resolve spontaneously, suggesting the delayed phase could be eliminated to reduce radiation exposure.
Endoleaks seen in one CT phase may resolve more often; leaves open whether delayed-phase imaging can be safely omitted after EVAR.
OBJECTIVE: The purpose of this study was to evaluate the clinical significance of endoleaks detected on combined arterial and delayed contrast-enhanced follow-up CT examinations of patients who have undergone endovascular aneurysm repair of abdominal aortic aneurysm. MATERIALS AND METHODS: One hundred forty-four patients underwent periodic follow-up CT examinations 12-72 months after abdominal aortic aneurysm repair. The CT protocol consisted of an unenhanced scan and contrast-enhanced scans in the arterial and 90-second delayed phases. The endoleaks detected on dual-phase CT scans were evaluated in association with the outcome (therapeutic intervention or endoleak resolution). RESULTS: The 144 patients underwent 728 CT examinations with a mean follow-up period of 35.5 +/- 14.5 months. Fifty endoleaks were detected in 50 (34.7%) of the patients. Eight endoleaks were detected in the arterial phase only, eight in the delayed phase only, and 34 in both phases. Intervention was performed to manage 16 endoleaks detected in both phases. CT showed that three endoleaks were stable (two in the arterial phase only and one in both phases) and that 31 had resolved completely (six in the arterial phase only, eight in the delayed phase only, and 17 in both phases). This finding represents a higher frequency of resolution of endoleaks detected in one phase only than in both phases (Fisher's exact test, p = 0.006). CONCLUSION: Endoleaks detected only in the delayed phase of CT had resolved spontaneously without intervention. Therefore, we can consider eliminating the delayed phase of acquisition to minimize radiation exposure.
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Hong et al. (2008) conducted an observational in Abdominal aortic aneurysm post endovascular repair (n=144). Endoleak detection in one phase only (arterial or delayed) vs. Endoleak detection in both phases was evaluated on Resolution of endoleaks (p=0.006). Endoleaks detected in only one phase of follow-up CT (arterial or delayed) had a significantly higher rate of spontaneous resolution than those detected in both phases (87.5% vs 50.0%; p=0.006).
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