Key result
Laparoscopic nephrectomy in 12 patients with refractory hypertension resulted in a complete response in 8 patients (66.7%), partial response in 3, and no response in 1.
Why the study?
Does laparoscopic nephrectomy improve refractory hypertension in patients with poorly functioning kidneys?
Observational (n=12)
Does laparoscopic nephrectomy improve refractory hypertension in patients with poorly functioning kidneys?
Laparoscopic nephrectomy may be an effective treatment option for refractory hypertension in carefully selected patients with non-functioning kidneys.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for laparoscopic nephrectomy in refractory hypertension with non-functioning kidneys; larger prospective studies needed before clinical adoption.
INTRODUCTION: Hypertension is a common medical problem mainly treated by effective antihypertensive drugs. Persistent hypertension can be difficult to manage and have detrimental effect on vital organs. Nephrectomy of poorly functioning kidneys may be indicated in a minority of such cases. PATIENTS AND METHODS: We performed laparoscopic nephrectomy on 12 patients with refractory hypertension. RESULTS: Eight had complete response, three had partial response and one had no response. CONCLUSIONS: Laparoscopic nephrectomy has a role in carefully selected adult patients with refractory hypertension due to non-functioning kidney. Patients need to understand the surgical risks as well as the small risk of failure to treat hypertension.
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Elhage et al. (2010) conducted an observational in Refractory hypertension due to poorly functioning kidneys (n=12). Laparoscopic nephrectomy was evaluated on Response to treatment (complete, partial, or no response). Laparoscopic nephrectomy in 12 patients with refractory hypertension resulted in a complete response in 8 patients (66.7%), partial response in 3, and no response in 1.
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