Key result
Delaying surgery for acute type A aortic dissection to treat hepatitis C led to acute-on-chronic dissection with trachea compression, requiring emergency surgery and causing residual dyspnoea.
Case Report (n=1)
Delaying surgery for acute type A aortic dissection may result in progressive aortic arch distension causing adjacent structure compression, such as tracheal compression and phrenic nerve injury.
Delaying repair for hepatitis C in acute type A aortic dissection may cause tracheal compression; this case leaves open optimal timing when comorbidities coexist.
An aortic dissection is a condition resulting from a tunica intima tear of the aortic wall creating a 'false lumen'. An acute Stanford type A (involves the aortic arch and/or ascending aorta) aortic dissection requires emergency surgical repair. To our knowledge, we report the first case in the literature where the treatment for an acute type A aortic dissection was intentionally delayed. This was decided following a multidisciplinary team discussion where it was agreed that the patient's active hepatitis C infection should be treated prior to surgery. The patient re-presented to the hospital 4 months later with acute dyspnoea and orthopnoea where he was diagnosed with an acute-on-chronic type A aortic dissection with trachea compression. This was successfully treated with emergency surgery. However, the patient suffered residual dyspnoea, likely due to phrenic nerve injury demonstrating the impact of untreated aortic arch distension on the neighbouring trachea and phrenic nerve.
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Ahmed‐Issap et al. (2022) conducted a case report in Acute Stanford type A aortic dissection and acute hepatitis C cryoglobulinaemia (n=1). Delayed surgical strategy was evaluated. Delaying surgery for acute type A aortic dissection to treat hepatitis C led to acute-on-chronic dissection with trachea compression, requiring emergency surgery and causing residual dyspnoea.
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