The accumulation of vitamin K in the plasma of healthy persons ingesting 2-100 g of natto was dose dependent. Ingesting natto bacilli (B. subtilis natto) also resulted in a rise of vitamin K concentration in the plasma. It was better for vitamin K retention in the plasma than the ingestion of standard natto product. This means that the natto bacilli influences vitamin K production in the digestive system. In both cases, there was no difference observed in the blood coagulation or fibrinolytic systems tested by TEG pattern and PT, APTT.
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Hiroyuki Sumi (1999) studied this question.
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