Key result
Mountain salt significantly lowers systolic and diastolic blood pressure compared to sea salt and NaCl.
Why the study?
Differences in chemical composition between mountain salt and sea salt and their effects on blood pressure have not been well characterized.
Does mountain salt solution reduce blood pressure compared to sea salt or NaCl solutions in WT C57BL/6J male mice?
Does mountain salt solution reduce blood pressure compared to sea salt or NaCl solutions in WT C57BL/6J male mice?
Mountain salt administration results in lower blood pressure compared to sea salt or pure NaCl in a mouse model, likely due to compositional differences including lower sodium chloride.
Mountain salt generally contains a lower amount of sodium chloride than that in sea salt, which is the commonly used salt. This study examined the differences in the chemical compositions of mountain and sea salts, and the effects of these compositional differences in mice. The compositions of reagent-grade NaCl, sea salt, and mountain salt were analyzed using an atomic absorption spectrometer and an energy-dispersive X-ray fluorescence spectrometer. Nine-week-old WT C57BL/6J male mice were administered distilled water (Cont), 2 % NaCl solution (NaCl), 2 % sea salt solution (Sea), or 2 % mountain salt solution (Mountain) for four weeks. Na, K, Ca, and Mg contents differed significantly between mountain salt and sea salt. At week 13, the systolic and diastolic blood pressures of mice in the Mountain group were significantly lower than those in the NaCl and Sea groups. Plasma creatinine levels and kidney fibrosis area ratios did not differ between the groups.
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Yamaoka et al. (2026) studied this question. Mountain salt solution vs. Distilled water, 2% NaCl solution, or 2% sea salt solution was evaluated on Systolic and diastolic blood pressures. Administration of a 2% mountain salt solution resulted in significantly lower systolic and diastolic blood pressures in mice compared to 2% NaCl and 2% sea salt solutions.
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