Answers are grounded in this paper and cite their sources.
[formula: see text] A method for the highly stereoselective synthesis of 1,3-amino alcohols based on the indium trichloride-catalyzed Mukaiyama aldol reaction of keto ester (R,S)-1 under solvent-free conditions has been developed. The high selectivity observed can be explained on the basis of the shielding of one face by a remote substituent.
No takes yet. Share an insight, caveat, or question.
Loh et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: