Key result
A history of heart failure was significantly associated with an increased risk of cardiovascular complications in critically ill patients with COVID-19 (OR 3.1).
Why the study?
Although COVID-19 primarily affects the respiratory system, it also impacts the cardiovascular system, prompting the need to determine cardiovascular complications in critically ill patients.
Observational (n=133)
Odds Ratio: 3.1 (95% CI 1.28–7.95)
p-value: p=0.02
In critically ill COVID-19 patients, cardiovascular complications are associated with prior heart failure, ARB use, older age, and elevated troponin, and are linked to high mortality.
May aid risk stratification in critically ill COVID-19; hypothesis-generating and requires prospective validation before practice change.
Introduction: The COVID-19 pandemic causes more than one million infected worldwide and thousands of deaths.Complications of this disease are in the respiratory system; however, the cardiovascular system is affected with complications including myocardial injury, myocarditis, myocardial infarction, heart failure, arrhythmias and venous thromboembolic episodes.Objective: To determine the cardiovascular complications associated with SARS-CoV-2 virus infection in critical patients. Materials and Methods:A retrospective, observational, transversal, analytical study was carried out, where 133 patients were included in the intensive care unit.Analytical statistics were performed using x2 for the qualitative variables and UMannwhitney for the quantitative variables of free distribution and t student for those of normal distribution.Multiple logistic regression was performed for the confounding variables.Results: Cardiovascular outcomes such as arrhythmias due to atrial fibrillation, heart failure or coronary thrombosis were associated with heart failure OR 3.1, 95% CI (1.28-7.95),history of treatment with Angiotensin receptor antagonist 2 OR 2.4, 95% CI (1.10-5.30),age over 60 years OR 2.7, 95% CI (1.20-6.20)Troponin I value over 0.205 ng/L OR 2.2, CI95% (1.04-5.37).Conclusions: Patients who had cardiovascular complications the mortality was high.
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Blanca Estela (2022) conducted an observational in COVID-19 in critically ill patients (n=133). History of heart failure vs. No history of heart failure was evaluated on Cardiovascular complications (arrhythmias, heart failure, or coronary thrombosis) (OR 3.1, 95% CI 1.28-7.95, p=0.02). A history of heart failure was significantly associated with an increased risk of cardiovascular complications in critically ill patients with COVID-19 (OR 3.1).
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