Left Ventricular Volume Reduction and Reshaping as a Treatment Option for Heart Failure
Key result
Combining structural and hemodynamic treatments is necessary to effectively reverse LV remodeling in HF.
Why the study?
Left ventricular remodeling propagates heart failure and progressive loss of ventricular function, making ventricular volume reduction and reshaping an important therapeutic target.
Design
Review
Authors
Discussion
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Member takes
Implication
Supports combining structural-hemodynamic therapies for LV remodeling in HF; leaves open confirmation in randomized trials.
Structured PICO
P
Population
Patients with chronic heart failure with reduced ejection fraction
I
Intervention
Treatments directed at structural and hemodynamic abnormalities for left ventricular volume reduction and reshaping
O
Outcome
Reversal of left ventricular remodeling
This review highlights the importance of combining treatments directed at structural and hemodynamic abnormalities to effectively reverse left ventricular remodeling in heart failure.
Cite This Study
Brener et al. (2020) conducted a review in chronic heart failure with reduced ejection fraction. Left ventricular volume reduction and reshaping treatments was evaluated. Combining treatments directed at structural and hemodynamic abnormalities is necessary to effectively reverse left ventricular remodeling in heart failure.