Key result
Primary hepatic angiosarcoma in an otherwise healthy man rapidly progressed to fulminant hepatic failure and death shortly after the onset of symptoms.
Case Report (n=1)
Highlights the rapid and fatal progression of primary hepatic angiosarcoma presenting as fulminant hepatic failure.
Prompts consideration of primary hepatic angiosarcoma in unexplained fulminant hepatic failure; case reports leave open early detection strategies.
Background. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short period of jaundice that progressed to fulminant hepatic failure. Methods. Case report and review of literature. Conclusion. This case illustrates the rapidity of progression to death after the onset of symptoms in a patient with hepatic angiosarcoma. Research on early diagnostic strategies and newer therapies are needed to improve prognosis in this rare and poorly understood malignancy with limited treatment options.
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Abegunde et al. (2015) conducted a case report in Primary hepatic angiosarcoma (n=1). Primary hepatic angiosarcoma was evaluated on Fulminant hepatic failure and death. Primary hepatic angiosarcoma in an otherwise healthy man rapidly progressed to fulminant hepatic failure and death shortly after the onset of symptoms.
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