Key result
Age-standardized stroke mortality in Brazil dropped ~58% between 1990 and 2019.
Why the study?
Stroke has been the second major cause of death in Brazil for decades, and better understanding of epidemiological statistics and disease burden is crucial for effective disease management.
Observational
Yes
Answers are grounded in this paper and cite their sources.
Stroke mortality, incidence, and DALY rates in Brazil have significantly decreased from 1990 to 2019, providing crucial epidemiological data for public health planning.
Background Stroke has been the second major cause of death in Brazil in the last decades. A better understanding on epidemiological statistics as well as on the diseases burden is crucial for enabling stakeholders to better tackle the disease. Purpose This project aims to continuously monitor and evaluate the data sources on heart disease and stroke in Brazil to provide the most up-to-date information on the epidemiology of these diseases to Brazilian society annually. Methods This initiative is based on the Heart Disease & Stroke Statistics Update methodology of the American Heart Association, with the support of the Brazilian Society of Cardiology, the Global Burden of Diseases Brazil network and an international committee. The project incorporates official statistics provided by the Brazilian Ministry of Health and other government agencies, as well as data generated by other sources and scientific studies on heart disease, stroke, and other CVD, including GBD/IHME data. Results The age-standardized prevalence rates per 100.000 for ischemic stroke in 1990 was 1327,6 (1151.2 to 1516) and 870.1 (761.1 to 992.8) in 2019 representing a percent change of −34.5 (−36.7 to −0.3). The age-standardized prevalence rates for intracerebral hemorrhage in 1990 was 507.5 (438.9 to584.1) and 315.9 (275 to 361.4) in 2019 representing a percent change of −37.7 (−40.5 to −0.3). The age-standardized incidence rates for stroke in 1990 was 224.6 (201.6 to 251.8) and 127 (113.8 to 142.1) in 2019 representing a percent change of −43.5 (−44.7 to −0.4). the age-standardized mortality rates for stroke in 1990 was 137.8 (127.8 to 144) and 58.1 (52.6 to 61.8) in 2019 representing a percent change of −57.8 (−60.4 to −0.6). The age-standardized DALY rates for stroke in 1990 was 2959 (2829.6 to 3063) and 1219.6 (1142 to 1285.5) in 2019 representing a percent change of −58.8 (−61 to −0.6). Conclusion This project represents a fundamental step on a better understanding on the stroke epidemiology in Brazil. While we observed a significant decrease in mortality rates from 1990 to 2019, we also raise a concern on a possible shift for a plateau curve or even increased rates in the next years. Funding Acknowledgement Type of funding sources: Other. Main funding source(s): Brazilian Society of Cardiology
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Machline-Carrion et al. (2021) conducted an observational in Stroke. Time period (2019) vs. Time period (1990) was evaluated on Age-standardized mortality rates for stroke per 100,000 (percent change -57.8, 95% CI -60.4 to -0.6). From 1990 to 2019, age-standardized stroke mortality rates in Brazil decreased by 57.8% (95% CI -60.4 to -0.6), dropping from 137.8 to 58.1 per 100,000.
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