Key result
High versus low-volume postoperative saline yields no quantitative AKI data after cardiac surgery.
Why the study?
Acute kidney injury is a common complication after cardiac surgery, and perioperative intravenous fluid administration may be an important factor for preserving postoperative renal function.
May warrant minimizing CPB duration to reduce AKI risk; leaves open optimal thresholds in cardiac surgery.
Acute kidney disease (AKI) is a known complication following cardiac surgery seen in almost one third of patients (1-3). AKI increases morbidity and mortality and of course affects the financial burden. Age, sex, preoperative renal function, diabetes mellitus, postoperative hypoperfusion, chronic hypertension and prolonged cardiopulmonary bypass (CPB) time contribute in varying proportions for the development of renal injury following heart surgery (4,5). Although CPB time is an independent risk factor, off-pump coronary artery bypass grafting surgery can lead to AKI and many studies suggest that perioperative intravenous fluid administration could be considered also as an important factor for better preservation of postoperative renal function (6,7).
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Kanakis et al. (2019) studied Acute kidney injury following cardiac surgery. High versus low-volume postoperative saline administration vs. Low-volume administration was evaluated on Acute kidney injury. High versus low-volume postoperative saline administration following cardiac surgery was discussed in the context of acute kidney injury, but no quantitative results were reported in the abstract.
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