Key result
The presence of right coronary artery stenosis in patients undergoing CABG for left main coronary artery disease was associated with a non-significant increase in in-hospital mortality (12.6% vs 5.5%, p=0.32).
Why the study?
Does the presence of right coronary artery (RCA) stenosis increase morbidity and mortality in patients undergoing CABG for left main coronary artery (LMCA) disease?
Cohort (n=107)
No
Does the presence of right coronary artery (RCA) stenosis increase morbidity and mortality in patients undergoing CABG for left main coronary artery (LMCA) disease?
In patients undergoing CABG for LMCA disease, concomitant RCA stenosis is associated with a higher incidence of low output syndrome, though its impact on overall in-hospital mortality did not reach statistical significance in this cohort.
Background: The association of right coronary artery (RCA) stenosis in patients undergoing myocardial revascularization for left main coronary artery (LMCA) stenosis affects the prognosis. This study aimed to compare immediate results of patients with isolated LMCA stenosis and those with combined RCA stenosis. Patients and methods: We retrospectively evaluated 107 consecutive patients with LMCA disease who underwent coronary artery bypass grafts. The patients were divided into two groups: isolated LMCA stenosis (n = 36) and LMCA stenosis + RCA stenosis (n = 71). Different variables (preoperative, intra operative and post operative) were compared. Results: Patients with LMCA stenosis + RCA stenosis experienced higher prevalence of diabetes mellitus (p = 0.024) and smoker (p = 0.032). Also left ventricular EF was reduced (p = 0.004). Myocardial revascularization was more complete in patients with LMCA stenosis + RCA stenosis (p = 0.033), but in-hospital mortality rate was higher (12.6% vs 5.5%) in isolated LLMCA stenosis, but it did not reach statistical significance (p = 0.32). Except low output syndrome (LOS) that was frequent in presence of RCA stenosis (p = 0.026), no significant difference was found between groups for other complications. Conclusion: The presence of RCA stenosis in patients undergoing CABG for LMCA disease increases 30 day mortality but without significant impact on overall morbidities.
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Aithoussa et al. (2015) conducted a cohort in Left Main Coronary Artery (LMCA) Stenosis (n=107). Combined right coronary artery (RCA) stenosis vs. Isolated left main coronary artery stenosis was evaluated on In-hospital mortality (30-day mortality) (p=0.32). The presence of right coronary artery stenosis in patients undergoing CABG for left main coronary artery disease was associated with a non-significant increase in in-hospital mortality (12.6% vs 5.5%, p=0.32).
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