Key result
Prolonged QTc affects ~20% of HIV patients, associated with female gender, diabetes, and hypertension.
Population
802 unselected HIV-infected patients
Design
Cross-sectional
Authors
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Supports considering QTc screening in HIV patients with diabetes or hypertension; hypothesis-generating for HIV-specific contributions.
Cross-Sectional (n=802)
Prolonged QTc interval has a high prevalence (nearly 20%) in HIV-infected patients and is associated with traditional risk factors like female gender, diabetes, and hypertension, rather than HIV-specific factors or medications.
Reinsch et al. (2009) conducted a cross-sectional in HIV infection (n=802). HIV infection was evaluated on Prolonged QTc interval (>440 ms in men, >460 ms in women) (95% CI 17-23). In a cohort of 802 HIV-infected patients, the prevalence of prolonged QTc interval was 19.8% (95% CI 17-23) and was associated with female gender, diabetes mellitus, and arterial hypertension.
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