October 1, 2019The Senior Care Pharmacist
Aspirin Use for Primary Prevention of Cardiovascular Disease in Older Patients: A Review of Clinical Guidelines and Updated Evidence
Why the study?
The role of aspirin for primary prevention of CV disease in older adults is not well defined, resulting in inconsistent guideline recommendations.
Does aspirin prevent cardiovascular disease in older adults for primary prevention?
Population
Older patients assessed for primary prevention of CV disease
Comparison
Aspirin use vs comparator in trials and guidelines
Design
Literature review
Authors
Discussion
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Member takes
Implication
Individualized aspirin decisions for primary CVD prevention in older adults are advised; leaves open optimal risk thresholds in contemporary populations.
Structured PICO
Does aspirin prevent cardiovascular disease in older adults for primary prevention?
P
Population
Older adults (elderly population) without established cardiovascular disease (primary prevention)
I
Intervention
Aspirin
O
Outcome
Cardiovascular disease prevention and bleeding risk
Aspirin use for primary prevention of cardiovascular disease in older adults requires individualized decision-making balancing cardiovascular benefits against bleeding risks.
Cite This Study
Lewis et al. (2019) conducted a review in Cardiovascular disease primary prevention in older patients. Aspirin was evaluated. The role of aspirin for primary prevention of cardiovascular disease in older adults should be individualized based on patient risk factors, including cardiovascular risk and bleeding likelihood.