Green solvents: Cyclic carbonates (ethylene and propylene carbonate) make excellent, sustainable solvents for (S)-proline catalyzed cross-aldol reactions between ketones and aromatic aldehydes. With cyclohexanone as the enamine precursor, reactions in ethylene carbonate gave much better results compared to propylene carbonate, whereas with acetone as the enamine precursor, reactions in both solvents gave similar results.
No takes yet. Share an insight, caveat, or question.
North et al. (2009) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: