Key result
Noninvasive skin pulse spectral analysis enables rapid detection of cardiac autonomic neuropathy.
Why the study?
Does a PC-based noninvasive measurement system using STPB and spectral analysis accurately detect the onset of diabetic autonomic neuropathy?
Does a PC-based noninvasive measurement system using STPB and spectral analysis accurately detect the onset of diabetic autonomic neuropathy?
A PC-based noninvasive system using skin transient pulse blood and spectral analysis offers a less expensive method for detecting cardiac autonomic neuropathy compared to laser Doppler flowmetry.
May offer low-cost autonomic screening in diabetes; leaves open prospective validation before clinical adoption.
The IBM PC-based system and experimental results presented here describe a new approach to recording electrophysiological signals associated with the autonomic nervous system, and the detection of the changes in electrophysiological signals due to onset of diabetic autonomic neuropathy. The authors have shown that the skin sympathetic sudomotor activity has much lower amplitude due to the functional state of the ANS caused by the diabetic neuropathy. The skin transient pulse blood (STPB) amplitude over many sweeps is statistically correlated with the laser Doppler flowmetry amplitude, but the photoplethysmographic technique is less expensive. Spectral analysis of STPB in the frequency range 0.5-2 Hz enables the separate assessment of parasympathetic and sympathetic activities and the rapid detection of cardiac autonomic neuropathy.
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Prună et al. (1998) studied Diabetic autonomic neuropathy. PC-based noninvasive measurement of the autonomic nervous system was evaluated on Detection of changes in electrophysiological signals due to onset of diabetic autonomic neuropathy. A PC-based noninvasive measurement system using spectral analysis of skin transient pulse blood enables the separate assessment of parasympathetic and sympathetic activities and rapid detection of cardiac autonomic neuropathy.
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