Key result
Depression and anxiety are linked to markedly worse QoL in myocardial ischemia, stroke, and chronic pain.
Observational
Depression and anxiety significantly worsen self-evaluated quality of life in patients with stroke, chronic low back pain, and myocardial ischemia, highlighting the need to account for these symptoms in clinical studies.
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Depression screening merits consideration in QoL evaluations for these cohorts; leaves open whether treating mood symptoms improves outcomes.
The prevalence of anxiety disorders and depression is assessed as between 20 and 50% following stroke. Depressive persons tend to give their overall life situation a worse rating than their relatives or physicians because of negative cognitions. Nevertheless, research concerning Quality of Life (QoL) after stroke hardly ever takes into account the methodological bias of assessing QoL only by self-rating. The aim of this study was to point out the important relationship between depression, anxiety and the autoassessment of QoL. QoL was markedly affected in the poststroke patients and in the chronic low back pain and myocardial ischemia patients, and it was rated worst by the most seriously depressed subjects. Clinical studies focusing on the ever more significant evaluation criterion 'health-related QoL' after stroke should take into account the high prevalence of anxiety and depressive symptoms and their major influence on the patients' self-evaluated QoL.
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Frühwald et al. (2001) conducted an observational in Stroke, chronic low back pain, and myocardial ischemia. Depression and anxiety vs. Less depressed subjects was evaluated on Self-rated Quality of Life (QoL). Depression and anxiety were associated with markedly worse self-rated Quality of Life among poststroke, chronic low back pain, and myocardial ischemia patients.
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