Key result
Average blood pressure ≥140/90 mmHg after endovascular therapy was associated with higher restenosis rates compared to achieving target BP <140/90 mmHg (36.2% vs 18.2%, p<0.01).
Why the study?
Does achieving a target blood pressure of < 140/90 mmHg reduce event incidence in patients with peripheral artery disease following endovascular therapy?
Cohort
Does achieving a target blood pressure of < 140/90 mmHg reduce event incidence in patients with peripheral artery disease following endovascular therapy?
Achieving a target blood pressure of < 140/90 mmHg and managing diabetes are associated with significantly lower restenosis rates after endovascular therapy in patients with peripheral artery disease.
This study examined the associations between blood pressure (BP) and event incidence to define optimal BP after endovascular therapy (EVT) in patients who underwent EVT. BP was monitored every 6 months for 5 years, and the patients were divided into two groups by average BP: ≥ 140/90 mmHg and < 140/90 mmHg. The association of BP with several events was examined. Although no significant differences in total mortality were observed between the groups, restenosis rates were significantly higher among patients who did not achieve target BP (36.2%) than among those who did (18.2%) (p < 0.01). The percentage of patients with glycosylated haemoglobin > 7.0% was significantly higher among those who did not achieve target BP in the restenosis group (42.9%) than in the other group (10.8%) (p < 0.01). In the restenosis group, there was a significantly higher percentage of patients taking metformin (p < 0.01) than in the other group. Metformin seemed to be administered to patients with more severe diabetes mellitus. In conclusion, it is important to manage hypertension and diabetes to prevent restenosis after EVT.
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Sasaki et al. (2015) conducted a cohort in Peripheral artery disease following endovascular therapy. Average blood pressure ≥ 140/90 mmHg vs. Average blood pressure < 140/90 mmHg was evaluated on Restenosis (p=< 0.01). Average blood pressure ≥140/90 mmHg after endovascular therapy was associated with higher restenosis rates compared to achieving target BP <140/90 mmHg (36.2% vs 18.2%, p<0.01).
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