Key result
Chicken breed linked to varying maternal IBDV antibody titers amid circulating virulent and vaccine strains.
Cross-Sectional (n=698)
The study provides data on the seroprevalence and genetic variation of infectious bursal disease virus in different chicken breeds in South Korea, highlighting the presence of very virulent strains.
Data on breed-specific maternal antibodies and circulating virulent IBDV strains in Korean chickens are hypothesis-generating; prospective studies needed before guiding vaccination.
The strategy for infectious bursal disease (IBD) control and its success rate under field conditions depends on hygiene management, IBD field pressure, level, and variation in maternally derived IBD antibodies. This study investigated the level of IBD-specific antibody by ELISA and the prevalence of IBD virus by PCR in broilers, white-semi broilers, and Korean native chickens raised in Jeongeup, Jeonbuk. IBD-specific maternally derived antibodies were measured from 698 chickens and the mean titers of maternal antibodies were 3,572±1,402 in broilers, 1,262±762 in white-semi broilers, and 1,932±912 in Korean native chickens. At 2 weeks after vaccination, the geometric mean antibody titers of broiler, white-semi broiler, and Korean native chicken were 582±427 , 3255±1,080 , and 1,023±499 , respectively. According to sequence analysis of the variable virion protein 2 gene, 4 isolates were found to be very virulent IBDV, 9 isolates classical virulent, and 2 isolates intermediate plus vaccine strain.
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Kang et al. (2012) conducted a cross-sectional in Infectious bursal disease (IBD) (n=698). Infectious bursal disease virus exposure and vaccination was evaluated on IBD-specific maternally derived antibody titers and viral genetic sequence analysis. In 698 chickens, mean maternal antibody titers varied by breed, and sequence analysis of 15 isolates identified 4 very virulent, 9 classical virulent, and 2 vaccine strains of IBDV.
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