Key result
mFI-5 predicts mortality and postoperative complications as effectively as mFI-11 in geriatric surgical patients.
Why the study?
Certain NSQIP variables were removed leaving only 5 of the original 11 modified frailty index factors, and the predictive ability of this 5-factor index had not yet been evaluated in geriatric surgical patients.
Does the mFI-5 perform as well as the mFI-11 in predicting mortality, postoperative infection, and 30-day readmission in geriatric surgical patients?
Observational
Yes
Does the mFI-5 perform as well as the mFI-11 in predicting mortality, postoperative infection, and 30-day readmission in geriatric surgical patients?
The 5-factor modified frailty index is an effective and comparable alternative to the 11-factor index for predicting mortality and postoperative complications in geriatric surgical patients.
Supports simplified frailty assessment in geriatric surgery; leaves open prospective validation before changing risk-stratification practice.
BACKGROUND: The modified frailty index (mFI-11) is a National Surgical Quality Improvement Program (NSQIP)-based 11-factor index that has been proven to adequately reflect frailty and predict mortality and morbidity. In the past years, certain NSQIP variables have been removed from the database; as of 2015, only 5 out of the original 11 factors remain. While the predictive power and usefulness of this 5-factor index (mFI-5) has been proven in previous work, it has yet to be studied in the geriatrics population. The goal of our study was to compare the mFI-5 to the mFI-11 in terms of value and predictive ability for mortality, postoperative infection, and unplanned 30-day readmission for patients aged 65 years and older. METHODS: Spearman's Rho was calculated to compare the value, and unadjusted and adjusted logistic regressions were created for three outcomes in nine surgical subspecialties. Correlation coefficients were above .86 across all surgical specialties except for cardiac surgery. Adjusted and unadjusted models showed similar C-statistics for mFI-5 and 11. RESULTS: Overall predictive values of geriatric mFI-5 and mFI-11 were lower than those for the general population but still had effective predictive value for mortality and post-operative complications (C-Stat ≥ .7) and weak predictive value for 30-day readmission. CONCLUSIONS: The mFI-5 is an equally effective predictor as the mFI-11 in all subspecialties and an effective predictor of mortality and postoperative complication in the geriatric population. This index has credibility for future use to study frailty within NSQIP, within other databases, and for clinical assessment and use.
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Subramaniam et al. (2020) conducted an observational in Geriatric surgical patients. 5-factor modified frailty index (mFI-5) vs. 11-factor modified frailty index (mFI-11) was evaluated on Mortality, postoperative infection, and unplanned 30-day readmission. The 5-factor modified frailty index (mFI-5) was an equally effective predictor as the mFI-11 for mortality and postoperative complications (C-statistic ≥ 0.7) in geriatric surgical patients.
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