Key result
EP study identifies AF or flutter with LBBB aberrancy misdiagnosed as VT, with ~80% verapamil response.
Case Report (n=5)
Electrophysiologic testing is valuable for correctly identifying wide complex tachycardias misdiagnosed as ventricular tachycardia, such as atrial fibrillation or flutter with LBBB aberrancy.
May support electrophysiologic evaluation in ambiguous wide-complex tachycardia; case series leaves open verapamil role in larger cohorts.
Five patients were referred for electrophysiologic evaluation of nonsustained or sustained ventricular tachycardia. In each patient, the clinical rhythm disturbance was reproduced and identified as atrial fibrillation or flutter with left bundle branch block aberrancy. All five patients demonstrated enhanced or accelerated atrioventricular conduction through the normal atrioventricular nodal-His Purkinje pathway. This rapid conduction created an electrophysiologic substrate suitable to the preferential development of this less common form of aberration. Four of five patients responded well (ventricular rate control or reversion to sinus rhythm) to verapamil therapy. Electrocardiographic criteria for differentiating supraventricular tachycardia with aberration from ventricular tachycardia exist. Nevertheless, misdiagnosis of wide complex tachycardia remains common. Electrophysiologic testing plays an important role in correctly identifying these rhythms, assessing long-term prognosis, and choosing effective therapy.
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Trohman et al. (1991) conducted a case report in Atrial fibrillation and flutter with left bundle branch block aberration misdiagnosed as ventricular tachycardia (n=5). Electrophysiologic evaluation and verapamil therapy was evaluated on Response to verapamil therapy (ventricular rate control or reversion to sinus rhythm). Electrophysiologic evaluation identified atrial fibrillation or flutter with left bundle branch block aberrancy in 5 patients misdiagnosed with ventricular tachycardia, with 4 of 5 responding to verapamil.
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