Cyp3A4, Cyp3A5, and MDR-1 genetic influences on tacrolimus pharmacokinetics in renal transplant recipients

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Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients2004 · 446 citations
2. 2Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo2000 · 2,374 citations
3. 3The Banff 97 working classification of renal allograft pathology1999 · 3,059 citations
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