Key result
IV zanamivir resolves severe influenza myocarditis when oral oseltamivir malabsorption is suspected.
Why the study?
Prompt diagnosis and treatment are important in influenza-related myocarditis, and intravenous zanamivir may serve as an alternative to oral oseltamivir in severe cases or with intestinal malabsorption.
Intravenous zanamivir may be an effective alternative to oral oseltamivir for severe influenza-related myocarditis, particularly when intestinal malabsorption is suspected.
Answers are grounded in this paper and cite their sources.
May warrant consideration with suspected malabsorption; leaves open need for controlled trials in influenza myocarditis.
In patients with influenza-related myocarditis, prompt diagnosis and treatment are important. Intravenous zanamivir can be an alternative to oral oseltamivir, especially in severe cases and when drug intestinal malabsorption is suspected or proven.
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Mazzitelli et al. (2019) studied this question. Intravenous zanamivir successfully treated severe influenza A(H1N1)pdm09 myocarditis, serving as an alternative to oral oseltamivir when intestinal malabsorption is suspected.
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