Key result
Concomitant AF ablation during double valve replacement is linked to ~71% long-term sinus rhythm restoration.
Why the study?
Does concomitant surgical atrial fibrillation ablation improve sinus rhythm restoration and clinical outcomes in patients with AF undergoing double valve replacement?
Cohort (n=238)
No
Does concomitant surgical atrial fibrillation ablation improve sinus rhythm restoration and clinical outcomes in patients with AF undergoing double valve replacement?
Absolute Event Rate: 71.2% vs 8.5%
p-value: p=<0.01
Concomitant surgical AF ablation during double valve replacement is safe and significantly improves sinus rhythm restoration and heart function without increasing perioperative risk.
May support ablation consideration in double valve replacement with AF; leaves open effects on outcomes and need for randomized confirmation.
BACKGROUND: Current European Society of Cardiology Guidelines recommend concomitant atrial fibrillation (AF) ablation for all symptomatic patients undergoing other cardiac surgeries, but the safety and potential benefits of concomitant atrial fibrillation (AF) ablation at the time of double valve replacement (DVR: aortic and mitral valve replacement) remains unexamined. MATERIALS AND METHODS: We conducted a retrospective review of 238 patients with AF who underwent DVR with or without concomitant surgical ablation (Ablation group, n = 113; Non-ablation group, n = 125) at a single institute from April 2006 to September 2011. RESULTS: There were no significant group differences in early postoperative mortality and morbidity, late survival, and freedom from major cardiac and cerebrovascular events (MACCEs). However, the Ablation group exhibited higher rates of sinus rhythm restoration at discharge (86.7% vs. 5.6%, P < 0.01) and at last follow-up (71.2% vs. 8.5%, P < 0.01). Follow-up echocardiography demonstrated smaller left atrial dimension and higher ejection fraction in the Ablation group (both P < 0.01). CONCLUSION: Concomitant surgical ablation for AF did not increase perioperative mortality or morbidity in patients undergoing DVR, but significantly increased sinus rhythm restoration, improved heart function, and decreased oral anticoagulation requirements.
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Tong et al. (2018) conducted a cohort in Atrial fibrillation in patients undergoing double valve replacement (n=238). Concomitant surgical atrial fibrillation ablation vs. Double valve replacement without concomitant surgical ablation was evaluated on Sinus rhythm restoration at last follow-up (p=<0.01). Concomitant surgical AF ablation during double valve replacement significantly increased sinus rhythm restoration at last follow-up compared to no ablation (71.2% vs. 8.5%, P<0.01).
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