Key result
Fetal tricuspid valve malformation correlates with lower biventricular GLS, worsening rapidly with reduced pulmonary flow.
Why the study?
To explore the relationship between cardiac function and pulmonary flow characteristics in tricuspid valve malformation fetuses using conventional and speckle tracking echocardiography.
Does reduced or absent pulmonary flow correlate with worse biventricular dysfunction in fetuses with tricuspid valve malformation?
Comparison
TVM fetuses with normal pulmonary flow vs reduced or absent pulmonary flow vs controls
Design
Retrospective case-control study
Authors
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Reduced pulmonary flow was associated with faster biventricular strain decline in tricuspid valve malformation; leaves open whether fetal strain imaging refines risk stratification.
Observational (n=168)
Does reduced or absent pulmonary flow correlate with worse biventricular dysfunction in fetuses with tricuspid valve malformation?
p-value: p=< .05
Fetuses with tricuspid valve malformation and reduced or absent pulmonary flow exhibit greater impairment and more rapid deterioration of biventricular function during gestation.
Liu et al. (2021) conducted an observational in Tricuspid valve malformation (n=168). Tricuspid valve malformation (with or without reduced/absent pulmonary flow) vs. Normal controls was evaluated on Global longitudinal strain (GLS) and strain rate for both ventricles (p=< .05). Tricuspid valve malformation fetuses demonstrated significantly lower biventricular global longitudinal strain and strain rate than controls (P < .05), worsening rapidly with reduced pulmonary flow.
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