Key result
Combined QRISK3 and EULAR mSCORE linked to ~11-fold higher odds of carotid plaques in RA.
Why the study?
Because carotid plaques predict cardiovascular events in rheumatoid arthritis, the authors aimed to assess whether combining SCORE and QRISK3 algorithms identifies RA patients with carotid plaques.
Does the combined use of QRISK3 and mSCORE algorithms improve the identification of carotid plaques in patients with rheumatoid arthritis?
Population
865 consecutive RA patients without diabetes, chronic kidney disease, or cardiovascular events
Comparison
Combined QRISK3 and EULAR mSCORE algorithms for predicting carotid plaques
Design
Retrospective cohort study
Authors
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May support combined scoring for plaque detection in RA; leaves open prospective validation before clinical adoption.
Cohort (n=865)
Does the combined use of QRISK3 and mSCORE algorithms improve the identification of carotid plaques in patients with rheumatoid arthritis?
Odds Ratio: 10.6 (95% CI 5.13–22)
The combined use of QRISK3 and EULAR mSCORE algorithms effectively identifies rheumatoid arthritis patients at high risk for carotid plaques, aiding in cardiovascular risk stratification.
Corrales et al. (2020) conducted a cohort in Rheumatoid arthritis (n=865). Combined use of QRISK3 and EULAR mSCORE vs. Lower risk thresholds was evaluated on Presence of carotid plaques (OR 10.6, 95% CI 5.13-22.0). The combined use of QRISK3 ≥ 10% and EULAR mSCORE ≥ 5% strongly identified rheumatoid arthritis patients with carotid plaques (diagnostic OR 10.6; 95% CI 5.13-22.0).
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